Antioxidant activity and toxicity of ethylmethylhydroxypyridine succinate and edaravone: comparative in vitro experiment

The cytotoxic effect and antioxidant activity of ethylmethylhydroxypyridine succinate (EMHPS) and edaravone were compared in a concentration range of 5 – 5000 mM. The cytotoxic effect was assessed on the HEK293 cell line using the MTT test.

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Original and generic drugs: what does the clinician need to know?

In the review article modern approaches to testing and registration of generic drugs are discussed. The article presents the history of the formation of the methodology for testing generic drugs and the current legislation of the Russian Federation.

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